Local rodent information

Rodent control in South Carolina

Learn what to look for around your property, explore your city, and ask about an inspection or a quote.

Rodents in South Carolina: what to know

Around South Carolina

Conditions vary across the state. Choose your city below, then describe what’s happening around your home or business.

What to note

Where you see rodents, how long it has been going on, and anything you’ve already tried are the most useful details to mention.

A useful next step

Ask about an inspection, what treatment would involve, and whether follow-up visits are included. You don’t need to identify the problem yourself before getting in touch.

Local research

Rodents in South Carolina: what the public record shows

Before you compare quotes, it helps to know which rodents actually live in South Carolina, when they are busiest, and what the state figures look like. Everything below links to the agency or university page it came from.

Second-generation anticoagulants restricted effective February 1, 2025

Statewide rodenticide restriction

Brodifacoum, bromadiolone, difethialone and difenacoum: dealer license required, sales limited to certified commercial, noncommercial and private applicators, with sales records kept.

Clemson University Department of Pesticide Regulation

High potential for adverse effects on non-target wildlife

Why the restriction was issued

Clemson forestry and environmental conservation research documented deaths in animals that eat poisoned rodents.

Clemson University Department of Pesticide Regulation

Roof rats only

Coastal rodent found in a Clemson monitoring study

On Kiawah Island a Clemson entomologist reported roof rats as the only rodent recorded, with mice largely absent.

Clemson University Cooperative Extension

Rodent species recorded in South Carolina

House mouse (Mus musculus) — Enters at 1/4 inch; 5-10 litters per year; eats about 200 small meals a night.
Norway rat (Rattus norvegicus) — Burrowing rat of basements, sewers and ground floors; tail shorter than head plus body.
Roof rat (Rattus rattus) — Climber of attics and trees in warm and coastal regions; tail longer than head plus body.

South Carolina is one of the few states with a statewide second-generation anticoagulant restriction, so coastal roof rat work leans on exclusion and trapping.

Rules that apply in South Carolina

South Carolina SGAR restriction (Clemson Department of Pesticide Regulation)

For context, nationally

1/4 inch (the width of a pencil) — Smallest gap a mouse can enter. CDC
890; 35% fatal; 94% west of the Mississippi — Hantavirus cases reported since 1993 (through 2023). CDC

Sources: Clemson University Department of Pesticide Regulation; Clemson University Cooperative Extension; CDC; Pest Notes: House Mouse; Pest Notes: Rats. Figures are quoted as the source prints them. How we check our sources

Explore South Carolina cities

Aiken

Humid Subtropical · rural setting

Rodent control in South Carolina

Rodents in South Carolina: what to know

Around South Carolina

What to note

A useful next step

Rodents in South Carolina: what the public record shows

Rodent species recorded in South Carolina

Rules that apply in South Carolina

For context, nationally

Explore South Carolina cities

Aiken

Anderson

Charleston

Columbia

Florence

Goose Creek

Greenville

Greer

Hilton Head Island

Mount Pleasant

Myrtle Beach

North Charleston

Rock Hill

Spartanburg

Summerville

Sumter

Taylors

Greenwood

Ask about rodent control in South Carolina